Genomic Diversity and Evolution of the Fish Pathogen Flavobacterium psychrophilum

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Genomic Diversity and Evolution of the Fish Pathogen Flavobacterium psychrophilum

Flavobacterium psychrophilum, the etiological agent of rainbow trout fry syndrome and bacterial cold-water disease in salmonid fish, is currently one of the main bacterial pathogens hampering the productivity of salmonid farming worldwide. In this study, the genomic diversity of the F. psychrophilum species is analyzed using a set of 41 genomes, including 30 newly sequenced isolates. These were...

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Nation-wide and local diversity of the fish pathogen Flavobacterium psychrophilum in Japan revealed by MLST analysis

Flavobacterium psychrophilum is the causative agent of bacterial cold-water disease (BCWD) and rainbow trout fry syndrome in salmonid fish. In Europe and in North and South America, F. psychrophilum usually affects salmonid hosts such as rainbow trout (Oncorhynchus mykiss) and coho salmon (Oncorhynchus kisutch). However, in Japan, ayu (Plecoglossus altivelis altivelis) are more frequently affec...

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Isolation and characterization of bacteriophages infecting the fish pathogen Flavobacterium psychrophilum.

Flavobacterium psychrophilum is a serious pathogen in trout aquaculture, responsible for the diseases rainbow trout fry syndrome (RTFS) and cold water disease (CWD). Bacteriophage control of F. psychrophilum may constitute a realistic approach in the treatment of these diseases; however, a detailed understanding of the phage-host interactions is needed to evaluate the potential of F. psychrophi...

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Transcriptional Responses of Resistant and Susceptible Fish Clones to the Bacterial Pathogen Flavobacterium psychrophilum

Flavobacterium psychrophilum is a bacterial species that represents one of the most important pathogens for aquaculture worldwide, especially for salmonids. To gain insights into the genetic basis of the natural resistance to F. psychrophilum, we selected homozygous clones of rainbow trout with contrasted susceptibility to the infection. We compared the transcriptional response to the bacteria ...

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Development of genetic techniques for the psychrotrophic fish pathogen Flavobacterium psychrophilum.

Flavobacterium psychrophilum, a member of the Cytophaga-Flavobacterium-Bacteroides group, is an important pathogen of salmonid fish. Previous attempts to develop genetic techniques for this fastidious, psychrotrophic bacterium have met with failure. Here we describe the development of techniques for the genetic manipulation of F. psychrophilum and the identification of plasmids, selectable mark...

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ژورنال

عنوان ژورنال: Frontiers in Microbiology

سال: 2018

ISSN: 1664-302X

DOI: 10.3389/fmicb.2018.00138